Priya, S. and Kaviyarasan, T. and Palaniappan, A. and Sheela, B. (2013) Nitric Oxide Releasing Photoresponsive Nanohybrids As Excellent Therapeutic Agent for Cervical Cancer Cell Lines. ACS Applied Materials and Interfaces, 5. pp. 8263-8266. ISSN 1944-8244

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Gold nanoparticles (GNPs) that can release nitric oxide (NO) on visible-light irradiation were prepared using 2-mercapto-5-nitro benzimidazole (MNBI) as stabilizer. These nanoparticles meet overall prerequisites for biomedical applications like small sizes, water solubility, and stability. It was found that even a very low dosage of MNBI-stabilized GNPs exhibit appreciable tumor cell mortality against cervical cancer cell lines, demonstrating the role of NO in killing cancer cells

Item Type: Article
Uncontrolled Keywords: photoresponsive;nanohybrids; 2-mercapto-5-nitrobenzimidazole (MNBI); gold nanoparticles (GNP); nitric oxide (NO); apoptosis
Subjects: Electrodics and Electrocatalysis
Depositing User: Dr. N Meyyappan
Date Deposited: 05 Jan 2015 05:14
Last Modified: 05 Jan 2015 05:14

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